Use of resources and costs associated with the treatment of Dupuytren’s contracture at an Orthopedics and Traumatology Surgery department in Denia (Spain): Collagenase Clostridium Hystolyticum versus subtotal fasciectomy
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Use of resources and costs associated with the treatment of Dupuytren’s contracture at an orthopedics and traumatology surgery department in Denia (Spain): collagenase clostridium hystolyticum versus subtotal fasciectomy
BACKGROUND Our purpose was to analyze and compare the use of direct health resources and costs generated in the treatment of Dupuytren's contracture using two different techniques: subtotal fasciectomy and infiltration with Collagenase Clostridium Histolyticum (CCH) in regular clinical practice at the Orthopedic and Traumatology Surgery (OTS) Department at the Hospital de Denia (Spain). METHO...
متن کاملPalmar fasciectomy after collagenase Clostridium histolyticum injection for Dupuytren’s contracture: A case report.
We present a case of successful salvage fasciectomy after initial collagenase Clostridium histolyticum (CCH) injection for the treatment of Dupuytren’s contracture. We did not find any remarkable scarring around the Dupuytren’s cord and nodule three and a half years after the initial CCH injection. Pathological findings revealed the previously ruptured cord and partial continuity of the collage...
متن کاملSafety and tolerability of collagenase Clostridium histolyticum and fasciectomy for Dupuytren’s contracture
Safety was evaluated for collagenase Clostridium histolyticum (CCH) based on 11 clinical trials (N = 1082) and compared with fasciectomy data in a structured literature review of 48 European studies (N = 7727) for treatment of Dupuytren's contracture. Incidence of adverse events was numerically lower with CCH vs. equivalent complications from fasciectomy (median [range] incidence), including ne...
متن کاملCosts for collagenase injections compared with fasciectomy in the treatment of Dupuytren's contracture: a retrospective cohort study
OBJECTIVES To compare collagenase injections and surgery (fasciectomy) for Dupuytren's contracture (DC) regarding actual total direct treatment costs and short-term outcomes. DESIGN Retrospective cohort study. SETTING Orthopaedic department of a regional hospital in Sweden. PARTICIPANTS Patients aged 65 years or older with previously untreated DC of 30° or greater in the metacarpophalange...
متن کاملMultiple Recurrences in Aggressive Forms of Dupuytren’s Disease—Can Patients Benefit from Repeated Selective Fasciectomy?
BACKGROUND In Dupuytren's disease (DD), limited fasciectomy is the mainstay of surgical therapy in patients at risk of contractures and disease recurrences. New minimally invasive treatments such as injection of collagenase clostridium histolyticum have evolved as a common tool for the preliminary treatment of Dupuytren's contractures. However, recurrences and their therapy remain controversial...
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